Replication process of the parvovirus H-1 V. Isolation and characterization of temperature-sensitive H-1 mutants
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چکیده
منابع مشابه
Isolation and preliminary characterization of temperature-sensitive mutants of poliovirus type 1.
We isolated six temperature-sensitive mutants of poliovirus type 1 (Mahoney) by hydroxylamine mutagenesis and replica plating at 31, 33 (permissive), and 39 degrees C (restrictive). One of these mutants, designated tsB9, was chosen for more detailed examination. tsB9 accumulated 25% of the wild-type amount of virus-specific RNA at the restrictive temperature. We found that tsB9 was not able to ...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1976
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.17.2.659-667.1976